A lightweight deep learning approach for detecting electrocardiographic lead misplacement.

OBJECTIVE: Electrocardiographic (ECG) lead misplacement can result in distorted waveforms and amplitudes, significantly impacting accurate interpretation. Although lead misplacement is a relatively low-probability event, with an incidence ranging from 0.4% to 4%, the large number of ECG records in clinical practice necessitates the development of an effective detection method. This paper aimed to address this gap by presenting a novel lead misplacement detection method based on deep learning models. APPROACH: We developed two novel lightweight deep learning model for limb and chest lead misplacement detection, respectively. For limb lead misplacement detection, two limb leads and V6 were used as inputs, while for chest lead misplacement detection, six chest leads were used as inputs. Our models were trained and validated using the Chapman database, with an 8:2 train-validation split, and evaluated on the PTB-XL, PTB, and LUDB databases. Additionally, we examined the model interpretability on the LUDB databases. Limb lead misplacement simulations were performed using mathematical transformations, while chest lead misplacement scenarios were simulated by interchanging pairs of leads. The detection performance was assessed using metrics such as accuracy, precision, sensitivity, specificity, and Macro F1-score. MAIN RESULTS: Our experiments simulated three scenarios of limb lead misplacement and nine scenarios of chest lead misplacement. The proposed two models achieved Macro F1-scores ranging from 93.42% to 99.61% on two heterogeneous test sets, demonstrating their effectiveness in accurately detecting lead misplacement across various arrhythmias. SIGNIFICANCE: The significance of this study lies in providing a reliable open-source algorithm for lead misplacement detection in ECG recordings. The source code is available at https://github.com/wjcai/ECG_lead_check.

Multi-branch myocardial infarction detection and localization framework based on multi-instance learning and domain knowledge.

Objective. Myocardial infarction (MI) is a serious cardiovascular disease that can cause irreversible damage to the heart, making early identification and treatment crucial. However, automatic MI detection and localization from an electrocardiogram (ECG) remain challenging. In this study, we propose two models, MFB-SENET and MFB-DMIL, for MI detection and localization, respectively.Approach. The MFB-SENET model is designed to detect MI, while the MFB-DMIL model is designed to localize MI. The MI localization model employs a specialized attention mechanism to integrate multi-instance learning with domain knowledge. This approach incorporates handcrafted features and introduces a new loss function called lead-loss, to improve MI localization. Grad-CAM is employed to visualize the decision-making process.Main Results.The proposed method was evaluated on the PTB and PTB-XL databases. Under the inter-patient scheme, the accuracy of MI detection and localization on the PTB database reached 93.88% and 67.17%, respectively. The accuracy of MI detection and localization on the PTB-XL database were 94.89% and 85.83%, respectively.Significance. Our method achieved comparable or better performance than other state-of-the-art algorithms. The proposed method combined deep learning and medical domain knowledge, demonstrates effectiveness and reliability, holding promise as an efficient MI diagnostic tool to assist physicians in formulating accurate diagnoses.

Finite-time cluster synchronization for complex dynamical networks under FDI attack: A periodic control approach.

In this paper, the finite-time cluster synchronization problem is addressed for complex dynamical networks (CDNs) with cluster characteristics under false data injection (FDI) attacks. A type of FDI attack is taken into consideration to reflect the data manipulation that controllers in CDNs may suffer. In order to improve the synchronization effect while reducing the control cost, a new periodic secure control (PSC) strategy is proposed in which the set of pinning nodes changes periodically. The aim of this paper is to derive the gains of the periodic secure controller such that the synchronization error of the CDN remains at a certain threshold in finite time with the presence of external disturbances and false control signals simultaneously. Through considering the periodic characteristics of PSC, a sufficient condition is obtained to guarantee the desired cluster synchronization performance, based on which the gains of the periodic cluster synchronization controllers are acquired by resolving an optimization problem proposed in this paper. A numerical case is carried out to validate the cluster synchronization performance of the PSC strategy under cyber attacks.